项目工作流程
| 阶段 |  |  | |
|---|---|---|---|
| 1. 评估准备阶段 | Instructions for preparing and shipping cells. | ||
| Assessment of cell line productivity: >30mg of antibody/Liter is required to proceed to scale-up, and a pilot fee will be charged. | |||
| Mycoplasma testing service. | |||
| Isotyping of cell culture supernatant. | |||
| 2. 细胞准备阶段 | Cell culturing and monitoring 7 days/week. | ||
| Freezing of five vials of cells. | |||
| Storage of cells at Bio X Cell for rapid re-supply. | |||
| Expansion of cells using optimized fermentation process. | |||
| Concentration of cell supernatant. | |||
| 3. 纯化抗体阶段 | Purification of supernatant on Protein A or G. | ||
| Buffer exchange to PBS that is preservative and stabilizer-free. | |||
| Sterile filtering of final product. | |||
| 
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| 4. 分装及质检阶段 | 
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| Internal antibody quality assessment. | |||
| Certificate of Analysis (CoA). | |||
| Murine pathogen screening service. | |||
| 5. 运输阶段 | Shipping on cold packs in environmentally friendly packaging. | 
 
                                                                        "我对 Bio X Cell 为我们提供的服务非常满意。当有人向我询问 CTLA-4 抗体时,我总是向您推荐。我期待着下一个 20 年。"
- James P.Allison
2018年诺贝尔生理学或医学奖共同获得者
